![Aortitis](/Upload/aortitis.jpg)
Aortitis
What are the symptoms?
Aortitis symptoms may be different
from person to person, depending on if they occur in the setting of an underlying
vasculitis or an associated inflammatory or infectious disease.
In some instances, people with
aortitis may not have any symptoms.
Aortitis symptoms may include:
Chest pain.
Stomach (abdominal) pain.
Back pain.
Headache.
Vision changes.
Fever.
Shortness of breath.
Swelling in your legs.
Pain in your arms or legs with use.
Symptoms of inflammation such as
decreased energy, weight loss or loss of appetite.
Symptoms related to vasculitis
affecting other blood vessels.
Symptoms related to an underlying
disease if this is present.
How else can aortitis affect my
body?
In addition to the symptoms they
have, people with aortitis can have complications, including:
Kidney failure.
Stroke.
Heart attack.
Heart failure.
Rupture or tearing of the aorta.
What causes aortitis?
Aortitis can occur as part of an
underlying systemic vasculitis or related to another inflammatory disease. In
these settings, the actual cause of the underlying disease and the associated
aortitis is unknown. Also, certain infections can cause aortitis.
Providers may find aortitis
unexpectedly at the time of aortic surgery. When aortitis isn’t associated with
another underlying disease or cause and it’s not affecting other blood vessels,
this is called “isolated focal aortitis.”
Systemic vasculitis and other
inflammatory disorders
Giant cell arteritis.
Takayasu arteritis.
Cogan syndrome.
Behçet disease.
Kawasaki disease (almost exclusively
affects children).
Polyarteritis nodosa.
Other forms of systemic vasculitis.
Ankylosing spondylitis.
Rheumatoid arthritis.
Systemic lupus erythematosus.
Relapsing polychondritis.
Sarcoidosis.
Immunoglobulin 4 (IgG4)-related
disease.
Inflammatory bowel diseases.
Infections
Salmonella.
Syphilis.
Staphylococcus.
Rocky Mountain spotted fever.
Gonococcal infection.
Tuberculosis.
Hepatitis B and C.
Herpes viruses.
Fungal infections.
How is aortitis diagnosed?
To make an aortitis diagnosis, your
healthcare provider will:
Talk to you about your medical
history.
Do a physical exam.
Order imaging tests to look at your
aorta and all of its major branches.
Order blood tests that can show a
high level of inflammation in your body.
Evaluate your aortic tissue under a
microscope if you’ve had surgery on your aorta.
What tests will be done to diagnose
aortitis?
Imaging tests for aortitis may
include:
Echocardiogram.
Transesophageal echocardiogram.
Abdominal ultrasound.
Computed tomography (CT).
Magnetic resonance imaging (MRI).
Positron emission tomography (PET).
Blood tests may include:
Erythrocyte sedimentation rate.
C-reactive protein.
Complete blood counts.
Chemistries to check kidney and
liver function.
Other blood tests to look for
systemic vasculitis, other inflammatory diseases or infection if necessary.
Aortic tissue examination:
If you’re having surgery for an
aortic aneurysm, your surgeon may take a tissue sample during surgery to check
for inflammation. Some people with no prior symptoms or signs of aortitis get
an aortitis diagnosis at the time of their aortic aneurysm surgery.
How is aortitis treated?
The treatment of aortitis can
include medication and/or surgery. Providers base their treatment decisions on:
Which part of your aorta the
condition affects.
If the aortitis is causing an
aneurysm or a narrowing and how severe this is.
Whether there’s an associated
disease or other underlying cause.
If it’s affecting other blood
vessels.
You may not need treatment if you
have isolated focal aortitis that a provider found and completely removed
during aortic surgery and there’s no underlying disease. In such settings,
ongoing monitoring remains extremely important to ensure there are no new
features that develop that may warrant a different approach.
What medications are used for
aortitis?
Your healthcare provider will use
medications when they identify an underlying active systemic vasculitis, other
inflammatory diseases or an infection. They may recommend:
Anti-inflammatory or
immunosuppressive medicines for systemic vasculitis or other underlying
inflammatory conditions.
Antibiotic drugs for aortitis associated
with an infection.
Are there side effects of these
treatments?
Immunosuppressive medications reduce
your body’s ability to fight an infection. Your healthcare provider will
discuss the risks and benefits of each treatment as well as strategies to
reduce these risks.
When do I need surgery for aortitis?
You may need surgery if you have:
An aortic aneurysm that’s
sufficiently large where there’s a concern for rupture or where the aneurysm is
affecting heart function.
A narrowing in your aorta that’s
seriously reducing blood supply to other vital body sites.